Therapeutic actions: Oseltamivir phosphate (Tamiflu) is in a new group of antiviral drugs called neuraminidase inhibitors. As the flu virus takes hold in the body, it forms new copies of itself and spreads from cell to cell. Neuraminidase inhibitors prevent the release of virus copies from the infected cells. Oseltamivir is a pro-drug which through metabolisation transforms into its active form.
Indications: Tamiflu is mainly used in treating virus influenza A and B( common cold, stomach flu, or other respiratory illness not caused by influenza virus)
Contraindications and cautions: If you have kidney disease, the doctor may have to cut your daily dose of Tamiflu in half. The effectiveness of Tamiflu has not been established for people with weakened immune systems. The drug has not been studied in people with liver disease. Tamiflu works only on the flu virus. It wonit stop bacterial infections that may have flu-like symptoms or bacterial infections that may develop while you have the flu. If your symptoms persist, check with your doctor.
Side effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Tamiflu will experience it or any other. Possible rare side effects that do not need to be reported to your doctor and should go away after a short period are: • headache • vomiting • difficulty falling asleep or staying asleep • diarrhea • nausea • dizziness • cough • stomach pain
More serious side effects that may need treatment could be:
• rash, hives, or blisters on the skin • hoarseness • itching • difficulty breathing or swallowing • swelling of the face or tongue The side effects listed above may not include all of the side effects reported by the drugis manufacturer. For more information about any other possible risks associated with Tamiflu, please read the information provided with Tamiflu or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Tamiflu. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe. Be sure to mention any of the following: medications that affect the immune system such as azathioprine - Imuran; cancer medications; sirolimus - Rapamune; methotrexate - Rheumatrex, cyclosporine - Neoral, Sandimmune oral steroids such as a smethylprednisolone - Medrol, dexamethasone - Decadron, Dexone, methylprednisolone - Medrol, and prednisone - Deltasone; or tacrolimus - Prograf, methotrexate -Rheumatrex.