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Proctosedyl (cinchocaine hydrochloride and hydrocortisone)
Proctosedyl (cinchocaine hydrochloride and hydrocortisone) is supplied as suppositories or as an odourless yellowish-white translucent greasy ointment. Each suppository or gram of ointment contains cinchocaine hydrochloride BP 5mg, hydrocortisone BP 5mg. The rationale of the combination is to combine the local anaesthetic, analgesic and spasmolytic effect of cinchocaine with the antipruritic and anti-inflammatory action of hydrocortisone. These ingredients are presented in emollient vehicles. Cinchocaine hydrochloride is a potent local anaesthetic agent with anti-pyretic properties resulting from its inhibition of the transmission of nerve impulses. It is recognised as being one of the longest acting of those agents commonly employed. It is included in PROCTOSEDYL for the relief of pain and spasm. Topical corticosteroids have anti-inflammatory, anti-pruritic and vasoconstrictive actions. Hydrocortisone is a low potency glucocorticoid which is safe and effective as a topical anti-inflammatory drug in the concentration employed in PROCTOSEDYL.
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