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Cytomel, T3 (Liothyronine Sodium)
Liothyronine is a naturally occurring hormone produced by the thyroid. It is important for normal energy and metabolism. For a variety of reasons, the body may not produce enough of this hormone on its own. In these cases, liothyronine is taken to replace the bodyis natural thyroid hormone.
Therapeutic actions: The mechanisms by which thyroid hormones exert their physiologic action are not well understood. These hormones enhance oxygen consumption by most tissues of the body and increase the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system.
What is it used for?: Cytomel is prescribed for treating low thyroid function. It is also used to treat or prevent different types of goiters, as an aid to diagnose certain thyroid conditions, or to treat patients who are allergic to other thyroid medicines. It may also be used for other conditions as determined by your doctor.
Contraindications and cautions: Thyroid hormone preparations are generally contraindicated in patients with diagnosed but as yet uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis and apparent hypersensitivity to any of their active or extraneous constituents. There is no well-documented evidence from the literature however, of true allergic or idiosyncratic reactions to thyroid hormone.
Side effects: Partial, temporary hair loss (children). Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); leg cramps; changes in appetite; changes in menstrual periods; changes in weight; chest pain; pounding in the chest; tremor; difficulty breathing; shortness of breath; excessive sweating; headache; inability to tolerate warm or hot room/weather conditions; increased heart rate; irregular heartbeat; nervousness; diarrhea; vomiting.
Interactions: The following medicines may interact with Cytomel: • Estrogen or birth control pills may decrease Cytomel is effectiveness. • Cytomel may increase the risk of side effects of anticoagulants (eg, warfarin), digitalis glycosides (eg, digoxin), ketamine, tricyclic antidepressants (eg, amitriptyline), or vasopressors (eg, norepinephrine). • Cytomel may decrease effectiveness of insulin or any other medicine for diabetes (eg, glyburide).